Journal Of Medicinal Chemistry

The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.

Some specific areas that are appropriate include the following:

* Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools.

* Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication.

*Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds.

* Molecular biological studies (e.g., site-directed mutagenesis) of macromolecular targets that lead to an improved understanding of molecular recognition.

*Computational studies that provide fresh insight into the SAR of compound series that are of current general interest or analysis of other available data that subsequently advance medicinal chemistry knowledge.

* Substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules.

* Effect of molecular structure on the distribution, pharmacokinetics, and metabolic transformation of biologically active compounds. This may include design, synthesis, and evaluation of novel types of prodrugs.

* Novel methodology with broad application to medicinal chemistry, but only if the methods have been tested on relevant molecules.

《Journal Of Medicinal Chemistry》是一本由AMER CHEMICAL SOC出版商出版的专业医学期刊，该刊创刊于1963年，刊期Semimonthly，该刊已被国际权威数据库SCIE、SCI收录。在中科院最新升级版分区表中，该刊分区信息为大类学科：医学 2区，小类学科：药物化学 1区；在JCR（Journal Citation Reports）分区等级为Q1。该刊发文范围涵盖药物化学等领域，旨在及时、准确、全面地报道国内外药物化学工作者在该领域取得的最新研究成果、工作进展及学术动态、技术革新等，促进学术交流，鼓励学术创新。2021年影响因子为8.039，平均审稿速度约2.1个月。

大类学科	分区	小类学科	分区	Top期刊	综述期刊
医学	1区	CHEMISTRY, MEDICINAL 药物化学	1区	是	否

JCR分区等级	JCR所属学科	分区	影响因子
Q1	CHEMISTRY, MEDICINAL	Q1	8.039

影响因子	h-index	Gold OA文章占比	研究类文章占比	OA开放访问	平均审稿速度
8.039	240	12.68%	99.81%	未开放	约2.1个月